CTEPH signs and symptoms

CTEPH symptoms are nonspecific¹:

• Indistinguishable from symptoms of other forms of pulmonary hypertension (PH)

• Can be mistaken for respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD)

On physical examination, initial findings consistent with CTEPH may include¹:

• A reduction in the splitting of the second heart sound (S₂)

• Accentuation of the sound of pulmonic closure (P₂)

• A palpable right ventricular heave

Subsequent findings correspond to decreasing right ventricular function¹:

• Jugular venous distention

• Fixed splitting of S₂

• Right-sided third heart sound (S₃)

• Tricuspid regurgitation

• Hepatomegaly, ascites, and peripheral edema