Patients with Inoperable CTEPH
In a 2011 registry of 679 CTEPH patients, 37% (247) were deemed inoperable1
According to the Fifth World Symposium on Pulmonary Hypertension that convened in 20132:
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All patients diagnosed with CTEPH should receive lifelong anticoagulation
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Comparing radiographic burden of disease with hemodynamics is critical to determining operability and risk from surgery before performing pulmonary thromboendarterectomy (PTE) (also called pulmonary endarterectomy [PEA])
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Overall operability assessment must consider patient factors, including comorbidities
Operability assessment remains a subjective process, so reevaluation of operability by a second experienced CTEPH center in cases initially deemed inoperable is recommended.2
References:
1. Pepke-Zaba J, Delcroix M, Lang I, et al. Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry. Circulation. 2011;124(18):1973-1981. 2. Kim NH, Delcroix M, Jenkins DP, et al. Chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol. 2013;62(suppl D):D92-D99.